Posts Tagged ‘Salk Institute’

Thursday January 26th, 2017

Scientists at Salk Institute have made breakthroughs in the integration of human cells into embryos of a different species

Human iPS cells (green) contributed to a developing heart of 4-week-old pig embryo (Image: Salk Institute)Scientists at Salk Institute for Biological Studies in California have made breakthroughs on multiple fronts in the race to integrate pluripotent stem cells from one species into the early-stage development of another. This will allow to study the embryonic development of an organism, diseases, test new therapeutic drugs and the possibly grow transplantable. Dr. Juan Carlos Izpisúa, professor in Salk’s Gene Expression Laboratory, leads this study published in today’s issue of the journal Cell. Dr. Josep M. Campistol, CEO and nephrologist in Hospital Clínic and researcher in IDIBAPS, and scientists from the Catholic University of Murcia (UCAM), the Pedro Guillén Foundation, the CEMTRO Clinic in Madrid and the University of Murcia, have also participated.

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Thursday December 15th, 2016

New cellular reprogramming technique counters hallmarks of aging

Scientists from Salk Institute for Biological Studies showed that One clue to halting or reversing aging lies in the study of cellular reprogramming, a process in which the expression of four genes known as the Yamanaka factors allows scientists to convert any cell into induced pluripotent stem cells (iPSCs) Like embryonic stem calls, iPSCs are capable of dividing indefinitely and becoming any cell type present in our body. Dr. Juan Carlos Izpisúa Belmonte, professor in Salk’s Gene Expression Laboratory, is the senior author of the paper, published in Cell, in which also participated Dr. Josep Maria Campistol, CEO and nephrologist in Hospital Clínic, and researcher in IDIBAPS. Scientists from Universidad Católica de Murcia, among others, have also been involved. Read the rest of this entry »

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Thursday August 25th, 2016

New method creates for the first time kidney progenitor cells that survive in the lab

Salk scientists, in collaboration with Dr. Josep Maria Campistol, CEO and nephrologist of Hospital Clínic and Marta Lazo, IDIBAPS researcher, have managed to create and maintain renal structures through the use of a 3D culture and a new combination of signaling molecules. It is the first time that researchers succeed in maintaining a culture of Nephron Progenitor Cells (NPCs), which is an important boost to translational medicine and to research on the development of kidney disease and a further step towards the possibility of creating a transplantable kidney . The study, led by Dr. Juan Carlos Izpisua Belmonte, professor in Salk’s Gene Expression Laboratory, has been published in the journal Cell Stem Cell.

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Friday April 24th, 2015

Gene-editing technique offers hope for hereditary diseases

Researchers from Hospital Clinic, IDIBAPS, Hospital Sant Joan de Deu of Barcelona and the Institute for Bioengineering of Catalonia (IBEC), have participated in a study led by scientists from the Salk Institute in La Jolla (California) where  molecular “scissors” have been used to remove mitochondrial mutations in mouse eggs cells. The study, led by Dr. Juan Carlos Izpisúa-Belmonte, Professor professor in Salk’s Gene Expression Laboratory, was published yesterday in the presitgious journal Cell.

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