Posts Tagged ‘Parkinson’

Friday July 29th, 2016

Mario Ezquerra and Rubén Fernandez-Santiago receive a grant from “The Michael J. Fox Foundation for Parkinson’s Research”

Dr. Mario Ezquerra and Dr. Ruben Fernandez-Santiago, researchers at the Neurodegenerative Diseases IDIBAPS team, have received a grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF). They are the principal investigators of the project MicroRNAs as biomarkers of the prodromal stage of Parkinson’s disease. The aim of this study is to evaluate the early deregulation of microRNAs in asymptomatic people at high risk of Parkinson’s disease. This project is part of the MJFF program named “Improved biomarkers and clinical outcome measures“, it will last two years with a budget of $ 215,000.

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Dr. Ruben Fernandez-Santiago receives the first “Young Researchers Grant” from the MINECO given to IDIBAPS

Dr. Ruben Fernandez-Santiago,  researcher at the Neurodegenerative Diseases IDIBAPS research team, has received a “Young Researchers Grant” from the Ministry of Economy and Competitiveness (MINECO), endowed with 170,000 Euros, to develop the study entitled “The beginnings of Parkinson Disease: a study of early disease mechanisms in a humanized in-vitro model“. This 3-year project aims to investigate early epigenetic alterations in dopaminergic neurons in people at high risk of Parkinson’s disease. This is the first time that an IDIBAPS researcher receives one of this grants, one of the four given in the neurosciences field in Spain.

The Young Researchers grants aim to fund projects led by young researchers who have a relevant scientific career.

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Thursday March 31st, 2016

A biopsy can diagnose Parkinson’s disease at an early stage in patients with sleep disorders

Researchers from Hospital Clínic and IDIBAPS have shown for the first time that it is possible to diagnose Parkinson’s disease (PD) in people with sleep disorders through a biopsy. This test is performed in the submandibular gland, located at the back of the mouth, and can detect a protein (alpha-synuclein) found in neurons of people with this disease. The prestigious journal The Lancet Neurology publishes the results of the study, led by the Unit of Parkinson’s Disesase at the Neurology Department in Hospital Clinic, and it is coordinated by Dr. Eduard Tolosa, researcher from CIBERNED and professor at the University of Barcelona. In the study several medical and surgical units form different departments of the Hospital Clinic have taken part.

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Monday December 21st, 2015

Spanish scientists discover changes in the target neurons of Parkinson’s disease

IDIBAPS researchers in collaboration with CIBERNED scientists identify for the first time, in a study published in EMBO Molecular Medicine, numerous changes in the epigenome of patients with Parkinson’s disease. They have discovered epigenetic alterations in Parkinson’s disesase using a model of dopaminergic neurons.

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Wednesday December 03rd, 2014

The Clínic organized a conference with patients participating in a study on Parkinson promoted by the Michael J. Fox Foundation

The Unit of Movement Disorders at Hospital Clínic hosted in November the annual meetings of the Parkinson’s Progression Markers Project Initiative (PPMI) attended by the patients participating in the study and their families. The aim of this conference was to provide relevant information about the project and report about the current state of research on Parkinson’s Disease. The speakers in this conference were Dr. Eduard Tolosa, Dr. María José Martí and Dr. Alex Iranzo, neurologists at  the Unit of Movement Disorders and Unit on Sleep Disorders at the Clínic, and the associate director of the Michael J. Fox Foundation,  Vanessa Arnedo.

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Friday July 29th, 2011

REM sleep behaviour disorder is a risk factor for Parkinson’s disease

Dr. Alex Iranzo during the press meetingPatients suffering REM sleep behaviour disorders dream nightmares in which they are attacked and pursued, with the particularity that they express them by screaming, crying, punching and kicking while sleeping. Lancet Neurology has published the third consecutive work in five years about the relationship between this disorder and Parkinson’s disease. The first work showed in 2006 that 45% of patients who suffer this sleep disorder develop Parkinson’s disease and other neurodegenerative diseases caused by a lack of dopamine in the brain. The second article discovered that neuroimaging tests that measure dopamine in the brain, such as the brain SPECT, are useful to identify patients with REM sleep disorders with increased risk of developing a neurodegenerative diseases such as Parkinson’s disease.

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