Posts Tagged ‘IRB Barcelona’

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Wednesday June 07th, 2017

A small group of neurons modulates the amount of insulin that the pancreas must produce

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses. These neurons are sensitive to fluctuations in nutrients such as glucose, fatty acids and amino acids.

Now, a research project co-chaired by Marc Claret, at the August Pi i Sunyer Biomedical Research Institute – IDIBAPS, and Antonio Zorzano, at the Institute for Research in Biomedicine (IRB Barcelona), both members of the CIBERDEM network, reveals the connection between POMC neurons at the hypothalamus and the release of insulin by the pancreas and describes new molecular mechanisms involved in this connection. The researchers publish the study in Cell Metabolism and the first authors are Sara Ramírez and Alicia G. Gómez-Valadés, both at IDIBAPS. Read the rest of this entry »

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Thursday March 16th, 2017

IDIBAPS and IRB Barcelona researchers create viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine (IRB Barcelona) lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting  healthy tissues. The study, published today by the journal Nature Communications, is part of Eneko Villanueva’s work for his PhD and it is co-lead by Cristina Fillat, head of the Gene Therapy and Cancer Group at IDIBAPS, and Raúl Méndez, ICREA researcher at IRB Barcelona. Read the rest of this entry »

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Friday February 17th, 2017

PhD4MD Programme is launched to bring research closer to clinical practice

The Centre for Genomic Regulation (CRG), the August Pi i Sunyer Biomedical Research Institute (IDIBAPS), the Institute for Research in Biomedicine (IRB Barcelona) and the Vall d’Hebron Research Institute  (VHIR) launch the third year of the training programme “PhD for Medical Doctors – PhD4MD”. Read the rest of this entry »

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Tuesday January 17th, 2017

Researchers discover a protein that protects against fatty liver, the most common hepatic disease in Western countries

A team co-headed by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the IDIBAPS Biomedical Research Institute (part of the Hospital Clínic de Barcelona) has revealed the capacity of the CPEB4 protein to prevent fatty liver disease. This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease. The results have appeared in Nature Cell Biology this week.

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Friday February 19th, 2016

The second edition of a predoctoral programme for physicians enhances different facets of research

Following the success of the first edition of the PhD programme for physicians – PhD4MD, an initiative created by the Centre for Genomic Regulation (CRG), theAugust Pi i Sunyer Institute for Biomedical Research (IDIBAPS), the Institute for Research in Biomedicine (IRB Barcelona)and the Vall d’Hebron Research Institute (VHIR), the participating centres have now launched a second edition.

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Friday December 11th, 2015

Scientists in Barcelona discover a potential treatment for cirrhosis

Scientists headed by Raúl Méndez, ICREA research professor at the Institute for Research in Biomedicine (IRB Barcelona), and Mercedes Fernández, at IDIBAPS in Barcelona, reveal that the inhibition of CPEB4 protein may prevent the development of the abnormal blood vessels associated with cirrhosis. Pathological angiogenesis is one of the most serious complications in patients with cirrhosis and a key factor in the development and worsening of the disease. Consequently, many research efforts focus on identifying treatments for this condition. The results of the study have been published in the most recent issue of Gastroenterology.

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