Posts Tagged ‘Immunologia’

Wednesday May 21st, 2014

An UB research shows that cholesterol plays a key role in cell migration

From left to right, researchers Carles Enrich, Meritxell Reverter, Anna Álvarez Guaita, Ana García Melero, Carles Rentero and Elsa Meneses, at the Faculty of Medicine of UB.

A group of researchers led by professor Carles Enrich, Chief of  IDIBAPS‘ Endocytosis and Protein Intracellular Transit team and member of Cellular Biology, Immunology and Neurosciences UB Dept., have found that cholesterol plays a key role in cell mobility and tissue invasion. The results of the study prove that the accumulation of LDL cholesterol cells —the one carried by low-density lipoproteins— may play a crucial role in promoting cell mobility. On the contrary, high levels of HDL cholesterol —the one carried by high-density lipoproteins— may avoid cell propagation. This is a key study to better understand cancer metastasis, the process in which cancer cells invade healthy tissues, and foster the discussion on the relationship between cholesterol levels and cancer incidence. The paper is published in open access Cell Reports.

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Thursday January 15th, 2009

The CD5 Molecule Helps to Combat Septic Shock Caused by Fungi

Dr. Francisco Lozano and Dr. Jorge Vera

Septic shock is a serious medical condition caused by an infection that spreads in an uncontrolled manner throughout the body via the circulatory system. It produces severe inflammatory symptoms with cardiovascular failure caused by particularly virulent bacterial or fungal toxins in the blood. It is the main cause of death in intensive care units, with a mortality rate of between 30% and 50% of patients who suffer from it.

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