Posts Tagged ‘episodis psicòtics’

Friday January 10th, 2014

Psychiatrists and basic scientists describe a dysregulation of the peripheral endocannabinoid system in first psychotic episodes

The journal Neuropsychopharmacology, from the Nature group, recently published an article that describes a dysregulation of the main components of the peripheral endocannabinoid system in patients with a first psychotic episode, comparing them with a large sample of healthy controls. After controlling for age, gender, body mass index, and cannabis use, the patient group showed a significantly reduced expression of the main enzymes of endocannabinoid synthesis and increased expression of those degrading them. The subgroup of patients with a history of cannabis showed a significant lower expression of some markers, compared with the control group. The first author of the study is Dr. Miquel Bioque and the last one is Dr. Miguel Bernardo, both members of the Schizophrenia Unit of the Hospital Clinic and the IDIBAPS team Biological bases of psychiatric disorders and nuclear psychiatry.

Read the rest of this entry »

Comments Closed