Posts Tagged ‘Antoni Castells’

Tuesday July 19th, 2016

Hospital Clínic makes a commitment to the molecular diagnostic of solid tumors in clinical practice

Hospital Clínic de Barcelona goes one step forward in the molecular diagnosis of solid tumors with a single test that detects multiple mutations within 22 genes in patients with advanced lung cancer, melanoma and colorectal cancer. The implementation of this genetic test based on massive parallel sequencing technologies allows shortening the time of diagnosis and personalizing the treatment for each patient. With this test, the Medical Oncology department at Hospital Clínic, together with the Biomedical Diagnostic Center (CDB), positions at the forefront of the clinical application of this diagnostic tool in the Spanish public health system, because of the technology used and the number of genes and tumors analyzed.

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Thursday December 10th, 2015

Dr. Leticia Moreira awarded with the Ramon Margalef UB Prize to the best article published in a scientific journal

Dr. Leticia Moreira, specialist at the Gastroenterology Department at Hospital Clinic and researcher at the Gastrointestinal and Pancreatic Oncology  IDIBAPS team led by Dr. Antoni Castells, won the Ramon Margalef Prize awarded by the Social Council of the UB to the best article published in a scientific journal. Her research is focused on identifying Lynch syndrome -the most common hereditary form of colorectal cancer- in patients suffering from this disease and was published in the Journal of the American Medical Association (JAMA). The capability to better detect when the disease has a hereditary origin allows a more effective prevention in the patients’ relatives. The method proposed in the article has been applied to almost 2,000 colorectal cancer patients at Hospital Clínic, and has allowed diagnosing thirty-eight families with the syndrome, which will follow from now on the necessary preventive controls.

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Tuesday October 27th, 2015

International experts discuss about the importance of screening programs in the fight against colorectal cancer

International experts meet from 24 to 28 October in Barcelona at the European Congress of Gastroenterology (United European Gastroenterology Week) to discuss about the latest advances in research, diagnosis and treatment of digestive diseases. Special emphasis is placed on the fight against colorectal cancer, since, according to experts, Spain is lagging behind due to low deposit rates in screening programs. Dr. Antoni Castells, head of the Institute of Digestive and Metabolic Diseases (ICMDM) at Hospital Clinic of Barcelona, has been appointed United European Gastroenterology spokesperson on colorectal cancer screening programmes and is presenting today the results of his research in this field.

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Friday October 18th, 2013

Dr. Ángel Carracedo offers a IDIBAPS Seminar about new genomic strategies against colorectal cancer

Colorectal cancer is related with heritability in around 30% of cases, but only 5% of genetic variance can be attributed to highly penetrant mutations. Thus, the investigators fighting the disease face a very complex problem which can only be solved using the latest genetics and bioinformatics technologies. Dr. Ángel Carracedo, Director of the Centro Nacional de Genotipado (CenGen-ISCIII) at Universidad Santiago de Compostela, is one of these investigators exploring all the opportunities to disclose the key pathways of colorectal cancer. He shared his experience in a IDIBAPS Seminar hosted by Dr. Antoni Castells, which was held in October 14th and entitled: New genomic strategies for the identification of genes involved in colorectal cancer.

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Thursday July 18th, 2013

Two IDIBAPS works among the Gastroenterology most cited articles between 2009-2012

Gastroenterology is the premiere journal in the field of gastroenterology and hepatology. It recently published a ranking of the top 10 most cited articles by Scopus for 2009-2012. Among the list of the most influential works published in Gastroenterology in recent years you will find two original papers led by investigators from the IDIBAPS teams Liver hemodynamics and portal hypertension, directed by Dr. Jaume Bosch, and Gastrointestinal and pancreatic oncology, directed by Dr. Antoni Castells.

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Tuesday July 09th, 2013

Criteria of postsigmoidoscopy referral to colonoscopy to fight colorectal cancer differ in terms of accuracy and resources needed

Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related death. Both fecal occult blood testing and flexible sigmoidoscopy have been shown to reduce colorectal cancer specific mortality and incidence. The IDIBAPS team Gastrointestinal and pancreatic oncology, led by Dr. Antoni Castells, Director of the Hospital Clínic Digestive and Metabolic Diseases Institute and professor at the University of Barcelona, has compared the existing strategies of postsigmoidoscopy referral to colonoscopy in terms of accuracy and resources needed. The results, based on data collected by the COLONPREV study, were recently published in the Journal of the National Cancer Institute, with Dr. Xavier Bessa, from Hospital del Mar, as its co-first author.

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