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Monday December 11th, 2017

Moderate exercise training improves some of the Marfan syndrome symptoms in mice

Regular physical activity is a common therapy for people with cardiovascular problems, but not recommended to those with Marfan syndrome, a rare disease of the connective tissue, but mainly affecting the cardiovascular system. A study conducted jointly by the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) has analysed for the first time this medical recommendation analysing the impact of exercise in the development of the disease in mice. The results, published in the scientific journal Journal of the American Heart Association, show that moderate exercise reduces the progression of the aortic aneurysm, one of the most severe symptoms of the disease which can cause arteries to break. Read the rest of this entry »

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Thursday November 30th, 2017

IDIBAPS hosts the annual meeting of the European AIDS Vaccine Initiative (EAVI2020)

At the beginning of November, scientists from 22 institutions in Europe, Australia, Canada and the United States, which are part of the European AIDS Vaccine Initiative 2020 (EAVI2020), met in Barcelona to analyze the latest advances in the development of an effective vaccine against HIV within the framework of the European Research and Development Program Horizon 2020. The three Spanish centers participating in this consortium are the IDIBAPS, organizer of the meeting, the IrsiCaixa AIDS Research Institute and the Institute of Health Carlos III. In the context of the meeting a photo exhibition entitled “The development of an HIV vaccine in photos” was presented, with the aim of sharing the scientific advances at the community level. This exhibition can be visited at the Hospital Clínic of Barcelona until February 2018. Read the rest of this entry »

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Thursday October 26th, 2017

Computational Simulations Suggest Multiple Sclerosis is a Single Disease

IDIBAPS researchers publish a study in the journal Plos Computational Biology that supports the idea that multiple sclerosis (MS), which has widely varying symptoms and progression in different patients, is nonetheless a single disease with common underlying mechanisms. Pablo Villoslada, Head of the IDIBAPS group Pathogenesis and new treatments in Multiple Sclerosis, has coordinated the study. Ekaterina Kotelnikova, researcher at the same group, is the first author. Read the rest of this entry »

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Wednesday October 18th, 2017

Gisela Sugranyes awarded with a NARSAD Young Investigator Grant

The Brain and Behaviour Research Foundation has awarded a research grant to Gisela Sugranyes, 50/50 researcher at the Multimodal neuroimaging in high risk and early psychosis IDIBAPS research team. The ‘NARSAD 2017 Young Investigator Grant’ is endowed with 70,000 for two years and is one of the most prestigious awards given to young researchers in the field of neuroscience. In this case, the funds will be used in the study of psychosis, specifically in determining the role played by an alteration in glutamatergic transmission in the clinical and cognitive manifestations of the disorder. Read the rest of this entry »

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Monday October 09th, 2017

IDIBAPS researchers describe the mechanism by which SOX11 promotes relapses in mantle cell lymphoma

Researchers at IDIBAPS publish an article in the Blood journal in which they show the mechanism by which the transcription factor SOX11 participates in the dissemination and aggressiveness of mantle cell lymphoma. They have discovered that SOX11 promotes the creation of a protective environment that ensures survival and resistance to treatments of tumor cells. The study was coordinated by Dr. Virginia Amador, researcher at the Human and experimental functional oncomorphology IDIBAPS team. Read the rest of this entry »

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Monday June 26th, 2017

Jaume Bosch coordinates the guidance on the management of portal hypertensive bleeding in cirrhosis published in Hepatology

Hepatology, the official journal of the American Association for the Study of Liver Diseases, has published a practice guidance entitled Portal Hypertensive Bleeding in Cirrhosis: Risk Stratification, Diagnosis, and Management. The study is coordinated by Dr. Jaume Bosch, hepatologist at Hospital Clínic and head of the research team Liver hemodynamics and portal hypertension at IDIBAPS. The other three authors, Dr. Juan G. Abraldes and Dr. Annalisa Berzigotti, are former IDIBAPS researchers, and Dr. Guadalupe Garcia-Tsao made a stay at this institution. The main newness of this guidance is the adaptation of the treatments to the various phases of cirrhosis. Read the rest of this entry »

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