Vídeo Clínic-UB sobre què és la Malaltia de Chagas i per què és un problema global. Read the rest of this entry »
The proportion of women who study medicine and who hold posts in resident programs for medical specialization has increased considerably in the past 3 decades. They currently represent 50% of practicing doctors and more than 80% of recently qualified doctors. A study published in the Journal of Medical Ethics and carried out in Hospital Sant Pau and Hospital Clínic, Barcelona shows that the proportion of women holding positions of responsibility in these hospitals represents only 13%, a figure which has remained constant between 2002 and 2006. The study was carried out by Dr. Amparo Santamaría of the hematology department of Hospital Sant Pau and Dr. Pilar Arrizabalaga of the nephrology department of Hospital Clínic, Barcelona, as first and second authors, respectively.
Amyloid is a pathologic substance mostly consisting of proteins such as amylin, which can become deposited on different organs and tissues. In some degenerative diseases, such as Alzheimer’s or Parkinson’s, the formation of ordered amyloid fibers has been observed in places where cell death occurs. In patients with type-2 diabetes mellitus, islets of amyloid have been found within the islets of Langerhans, the collection of pancreatic cells with an endocrine function. These amyloid deposits are found in regions with cellular degeneration and have therefore been associated with the progression of the diabetes.
An IDIBAPS study published on the front page of Diabetologia (51(12):2252-62) by the team led by Dr. Anna Novials analyzes the mechanisms by which these amyloid fibers are associated with the death by apoptosis of pancreatic cells. The results show that abnormal concentrations of calcium play a key role in the toxicity induced by the amyloid. The hypothesis put forward in the article suggests that TRPV4, a channel to the cell surface that is sensitive to mechanical and osmotic changes, becomes activated in response to physical alterations caused by the aggregation of fibers around the cells. This would activate the process that leads to cell death by apoptosis: the entry of calcium into the cell, that the polarized nation of the membrane, and the activation of L-type calcium channels.
Considerable disagreement persists regarding hospital-acquired pneumonia and ventilator-associated pneumonia. This circumstance has led to the initiative to create a consensus document that unifies the criteria of the 3 main European societies linked to these diseases—the European Respiratory Society (ERS), the European Society of Clinical Microbiology and Infectious Diseases and the European Society of Intensive Care Medicine. The person chosen to coordinate this project and represent the ERS was Dr. Antoni Torres, head of the respiratory medicine department of Hospital Clínic, Barcelona and leader of the research team on the spiritual diseases at the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). He is the principal author of the article published in the Journal Intensive Care Medicine (35:9-29), which lists the 20 points of agreement that were reached.
El Conseller Delegat del Clínic respon a les preguntes dels lectors de Diario Médico — El Consejero Delegado del Clínic respondo a las preguntas de los lectores de Diario Médi Read the rest of this entry »
The Institute for Health Care Research (IIS) Clínic-IDIBAPS is a new body that was created as a result of the accreditation of our center by the Ministry of Science and Innovation. The first scientific meeting under the umbrella of the strategic alliance, which joins the efforts of this new institute with those of the IRB, was held on 22 January. The theme of the meeting was cancer and this allowed scientists from IDIBAPS-Clínic and the IRB to share experiences and approaches during an intense conference held at the Barcelona Hilton Hotel.
The aim of this initiative is to encourage the creation of networks of cooperation between the two institutions. New themed meetings of this type will be held over the coming months. The 3 planned themes are: Neurosciences; hepatic and metabolic diseases; and Infectious diseases, research on international health and immunology. It is necessary to continue to join forces to make the research done in Barcelona, Catalonia and Spain increasingly competitive at international level.