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Friday April 03rd, 2009

Protein Trafficking to the Liposomes is Abnormal in Huntingdon Disease

Dr. Josep Maria canals and Daniel Del Toro at the UB Medicine Faculty

Huntingdon disease is a hereditary neurodegenerative disease that progressively and specifically destroys the cerebral cortex and basal ganglia, where the most affected cells are the neurons of the corpus striatum. This disease presents between the ages of 30 and 50 years and is characterized by cognitive and motor disorders. The most characteristic trait is exaggerated movement of the limbs, which lead to completely incapacitating behavior by the patient.

The disease is caused by a mutation of the huntingtin protein, which is widely distributed throughout the cells. Huntingtin is located in the Golgi apparatus and in the transport vesicles. It interacts with intracellular motors and allows movement of the vesicles within the cell. The mutation of the protein consists of an abnormal increase of more than 35 repetitions of glutamine at the N-terminal. The molecular mechanisms that lead this mutation of huntingtin to cause neuron dysfunction and death, particularly in neurons of the corpus striatum are not understood.

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Dr. Ribal is the First Woman to Receive the 2009 Urology Prize of the European Association of Urology

Dr. Ribal is the First Woman to Receive the 2009 Urology Prize of the European Association of UrologyThis is the first time that the European Association of Urology has given this award to a woman and the first time the award has been won by a Spaniard.  Dr. María José Ribal of the Hospital Clínic urology department received the 2009 Crystal Matula award, an international recognition of the scientific work of young people who have contributed to advances in urology. The prize was awarded on 19 March in Stockholm, Sweden, in a ceremony held at the 24th annual conference of the European Association of Urology. Dr. Ribal won the award for the innovative nature of her research in the field of urologic oncology, particularly bladder cancer.

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Thursday April 02nd, 2009

The Josep Carreras Foundation Sponsors a New Research Institute on Leukemia

Josep Carreras amb un jove pacient (imatge de ruben moreno).

An agreement of intentions signed this afternoon at the Catalan Government Palace presented the new International Research Institute on Leukemia (Institut Internacional de Recerca contra la Leucèmia), linked to the Josep Carreras Foundation. Taking part in the action were the President of the Catalan Government, José Montilla, the tenor Josep Carreras, the Catalan Minister for Health, Marina Geli, the Catalan Minister for Innovation, Universities and Enterprise, Josep Huguet and the Mayor of Badalona, Jordi Serra. Hospital Clínic de Barcelona and Hospital Germans Trias i Pujol, together with the Josep Carreras Foundation and the Catalan Government, will be the main sponsors of this initiative.

The new institute will be the first Spanish center, and one of only a few worldwide, dedicated exclusively to research on malignant blood diseases. The initiative is the result of three great efforts: the personal will of the tenor Josep Carreras, whose foundation has been fighting leukemia for more than 20 years; the excellent Catalan scientific standard in the field of hematology; and the support of the Catalan government in consolidating Catalonia as a pioneer in biotechnology and biomedicine.

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The Translational Research Group on Liver Cancer Receives the AACR INNOVATOR Award

Dr. Josep Maria Llovet The American Association of Cancer Research has awarded Dr. Josep Maria Llovet of the IDIBAPS Liver Cancer team with the 2009 Landon Foundation – AACR INNOVATOR Award for International Collaboration in Cancer Research. This prestigious award provides funding for large lines of collaborative research in cancer.

The translational research group led by Dr. Llovet is a paradigm of collaboration in network, as it takes part in many initiatives, such as the CIBER on Liver and Digestive Diseases (CIBERehd) and the HCC Genomic Project international consortium. Dr. Llovet himself combines his responsibilities as professor of ICREA research at the IDIBAPS and as director of the HCC Research Program at Mount Sinai School of Medicine in New York.

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Wednesday April 01st, 2009

Activation of the Prefrontal Cortex Improves Working Memory

Dr. Albert Compte leads the study on working memory

Working memory or short-term memory is related to the ability to pass intelligence tests and is stored in the parietal cortex. However, the role of other areas of the cortex which are activated during use of visual memory is poorly understood. An IDIBAPS team has programmed a complex virtual system that simulates a network of neurons, according to which the prefrontal cortex reinforces the activation of the parietal cortex. This makes is possible to increase the working-memory capacity when necessary. This hypothesis is confirmed by functional magnetic resonance data.

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Thursday March 26th, 2009

Online Encounter With Dr. Elias Campo

El Dr. Elies Campo ha estat avui al xat de Diario MédicoDr. Elias Campo, director of the Center for Biomedical Diagnosis (CDB) of Hospital Clínic de Barcelona was invited today, 26 March, to the “Encuentros Digitales” chat section of Diario Médico, an open participation space, where he answered the questions posed by the online users of this specialist publication. You can access the transcription of the chat via the following link: Diario Médico.

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