Archive for the ‘IDIBAPS’ Category

Thursday April 09th, 2009

Early Administration of Antiretroviral Therapy Can Improve Survival

 Dr. Josep Maria Miró during the pres meeting at the Hospital Clínic

The first antiretroviral treatments appeared in 1996. Since then, new and better drugs have been discovered that have almost turned AIDS into a chronic disease. Nevertheless, there is still room to improve the performance of the the therapeutic strategies used in clinical practice. This is shown by a study published in the online edition of The Lancet, suggesting that early administration of antiretroviral treatment reduces the rate of AIDS development and death in HIV-positive patients by 28%. This study analyzed information from more than 45,000 patients in Europe and North America and combined data from 15 international cohorts. One of these is the PISCIS Catalan and Balearic cohort, coordinated by Dr. Jordi Casabona of the Centre for Epidemiologic Studies of Sexually Transmitted Diseases and AIDS in Catalonia (CEEISCAT) – Catalan Institute of Oncology (ICO), and by Dr. Josep María Miró of the Infectious Diseases Department of Hospital Clínic – IDIBAPS, University of Barcelona. Dr. Josep María Miró is the only Spaniard in the international When to Start Consortium, which has taken part in writing and signing the article. Professor Jonathan Sterne of the University of Bristol (UK) is the first author.

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Monday April 06th, 2009

Psychoeducation is Beneficial in the Long Term in Bipolar Disorder

Dr. Eduard Vieta and Dr. Francesc Colom, second and first authors, respectively

A 6-month psychoeducational strategy achieves beneficial effects that last more than 5 years. Patients who took part in the psychoeducation sessions suffered 66% fewer episodes of mania and 75% fewer episodes of depression. This represents preventing a year of symptoms over 5 years. The cost-benefit analysis shows that the use of health care resources is far lower in these groups than in those that do not carry out the initial follow-up. Hospital Clínic de Barcelona is a pioneer both in the application of this treatment and in training professionals qualified to carry it out.

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Friday April 03rd, 2009

IIS Clínic-IDIBAPS Holds a Conference on Neurosciences in Conjunction with the IRB and Sant Joan de Déu

IIS Workshop Clínic-IDIBAPS on Neurosciences

Last week, on 26 and 27 March, the second meeting of the Clínic-IDIBAPS Institute for Health Care Research was held at the Hilton Diagonal hotel. On this occasion, the conference took a closer look at research in neuroscience, with the aim of exchanging knowledge with other pioneering centers such as the Barcelona Institute for Biomedical Research and Hospital Sant Joan de Déu. The conference dealt with different diseases (Alzheimer, Parkinson, schizophrenia and other neurodegenerative and psychiatric diseases) from the different levels of research, from basic to clinical, placing special emphasis on translational research.

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Protein Trafficking to the Liposomes is Abnormal in Huntingdon Disease

Dr. Josep Maria canals and Daniel Del Toro at the UB Medicine Faculty

Huntingdon disease is a hereditary neurodegenerative disease that progressively and specifically destroys the cerebral cortex and basal ganglia, where the most affected cells are the neurons of the corpus striatum. This disease presents between the ages of 30 and 50 years and is characterized by cognitive and motor disorders. The most characteristic trait is exaggerated movement of the limbs, which lead to completely incapacitating behavior by the patient.

The disease is caused by a mutation of the huntingtin protein, which is widely distributed throughout the cells. Huntingtin is located in the Golgi apparatus and in the transport vesicles. It interacts with intracellular motors and allows movement of the vesicles within the cell. The mutation of the protein consists of an abnormal increase of more than 35 repetitions of glutamine at the N-terminal. The molecular mechanisms that lead this mutation of huntingtin to cause neuron dysfunction and death, particularly in neurons of the corpus striatum are not understood.

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Dr. Ribal is the First Woman to Receive the 2009 Urology Prize of the European Association of Urology

Dr. Ribal is the First Woman to Receive the 2009 Urology Prize of the European Association of UrologyThis is the first time that the European Association of Urology has given this award to a woman and the first time the award has been won by a Spaniard.  Dr. María José Ribal of the Hospital Clínic urology department received the 2009 Crystal Matula award, an international recognition of the scientific work of young people who have contributed to advances in urology. The prize was awarded on 19 March in Stockholm, Sweden, in a ceremony held at the 24th annual conference of the European Association of Urology. Dr. Ribal won the award for the innovative nature of her research in the field of urologic oncology, particularly bladder cancer.

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Thursday April 02nd, 2009

The Josep Carreras Foundation Sponsors a New Research Institute on Leukemia

Josep Carreras amb un jove pacient (imatge de ruben moreno).

An agreement of intentions signed this afternoon at the Catalan Government Palace presented the new International Research Institute on Leukemia (Institut Internacional de Recerca contra la Leucèmia), linked to the Josep Carreras Foundation. Taking part in the action were the President of the Catalan Government, José Montilla, the tenor Josep Carreras, the Catalan Minister for Health, Marina Geli, the Catalan Minister for Innovation, Universities and Enterprise, Josep Huguet and the Mayor of Badalona, Jordi Serra. Hospital Clínic de Barcelona and Hospital Germans Trias i Pujol, together with the Josep Carreras Foundation and the Catalan Government, will be the main sponsors of this initiative.

The new institute will be the first Spanish center, and one of only a few worldwide, dedicated exclusively to research on malignant blood diseases. The initiative is the result of three great efforts: the personal will of the tenor Josep Carreras, whose foundation has been fighting leukemia for more than 20 years; the excellent Catalan scientific standard in the field of hematology; and the support of the Catalan government in consolidating Catalonia as a pioneer in biotechnology and biomedicine.

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