On May 21st the European consortium CATCH ME (Characterizing Atrial fibrillation by Translating into STI Health Causes Modifiers in the Elderly) was launched at the office of the European Society of Cardiology in Brussels. The aim of this project is to improve the prevention, diagnosis and treatment of patients with atrial fibrillation and its complications. Dr. Lluís Mont, coordinator of Atrial Fibrillation Unit of the Hospital Clinic of Barcelona, participates in this project, coordinated by the University of Birmingham (UK). Horizon 2020, which is the largest EU research and innovation programme, supports the consortium with a 5 Mio Euro grant over the consortium’s duration of 4 years.
Hospital Clínic participates in a European project for the prevention and treatment of atrial fibrillation
An IDIBAPS-Clínic study shows for the first time the benefits of the Google-Pubmed “big data” in systemic autoimmune diseases geoepidemiology
The big data is changing the landscape of scientific research, also in medicine, where in areas such as epidemiology and genetics allows analyzing total or almost total populations in studies that can be relatively basic (determine the impact of a specific disease in a population) or very complex (analyzing the effectiveness of new drugs on a whole population or large-scale genetic research).
Now a geoepidemiologic autoimmune study conducted on 394.827 patients with systemic autoimmune diseases (SAD) led by the Systemic Autoimmune Diseases IDIBAPS team, the Transverse Group for research in Primary Care from IDIBAPS and CAPSBE, and the Hospital Clínic, in co-operation with Tel Aviv University, King’s College University of London and the Harvard Medical School in Boston, shows the results of a massive data search using Google and Pubmed in combination, and the benefits that can be obtained for medical research on systemic autoimmune diseases (SAD). The study is available online in the journal Autoimmunity Reviews.
An article in the Journal JAMA Internal Medicine shows the benefits of the Mediterranean diet to prevent or delay cognitive impairment associated with aging that eventually ends in dementia or Alzheimer’s disease. The study, derived from PREDIMED nutritional intervention (Prevention with Mediterranean Diet) reveals that, after a 4 years follow-up, people who followed the Mediterranean diet supplemented with extra virgin olive oil or mixed nuts had better cognitive function than those allocated in the control low-fat diet. Dr. Emili Ros, from the Endocrinology and Nutrition Department of the Hospital Clínic and leader of the Hypertension, lipids and cardiovascular risk IDIBAPS team, has coordinated this work whose first author is Dr. Cinta Valls-Pedret, specialist in Neuropsychology at the Lipids Unit in Hospital Clínic.
A group of researchers from IDIBAPS and the Imperial College London have developed, for the first time, a collection of the genome regions that contain the instructions for the pancreas development in the human embryo. There are included both the genes and those regions of the genome, called enhancers, that act as a kind of switches and play a key role in the genes activation or deactivation. The analysis of these switches has revealed a new mechanism that promotes the formation of the pancreas. In the article, published in the journal Nature Cell Biology, a model of stem cells differentiated to pancreatic progenitor cells, has also been validated which will facilitate the study of this organ in vitro from now on. Dr. Jorge Ferrer, head of the Genomic Programming of Beta Cells and Diabetes team at IDIBAPS and the Imperial College London, coordinates this study in which has also participated Dr. Meritxell Rovira, researcher in the same group at IDIBAPS.
IDIBAPS has been recognized with the HR Excellence in Research label, within the framework of the action Human Resources Strategy for Researchers (HRS4R) of the European Commission (EC). This award is granted to research institutions that voluntarily implement improvements to their HR practices to get closer to the principles set out in the European Charter and Code for Researchers.
Researchers from Hospital Clinic, IDIBAPS, Hospital Sant Joan de Deu of Barcelona and the Institute for Bioengineering of Catalonia (IBEC), have participated in a study led by scientists from the Salk Institute in La Jolla (California) where molecular “scissors” have been used to remove mitochondrial mutations in mouse eggs cells. The study, led by Dr. Juan Carlos Izpisúa-Belmonte, Professor professor in Salk’s Gene Expression Laboratory, was published yesterday in the presitgious journal Cell.