Monday October 27th, 2014

New computational method allows the identification of genetic alterations in cancer patients within hours

IDIBAPS and Hospital Clínic have participated in the development of a new computational method that enables to detect genetic changes responsible for the onset and progression of tumors in a simple, quick and precise way. The research is published in the latest issue of the prestigious journal Nature Biotechnology. This methodology, called SMUFIN (Somatic Mutations Finder), is capable of analyzing the complete genome of a tumor and identifying its mutations in a few hours. In addition, it is able to identify alterations which had previously not been revealed, even using methods which require the use of supercomputers over several weeks.

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Friday October 17th, 2014

Hospital Clínic leads the new international guidelines for the treatment of Chronic Lymphocytic Leukemia

The Hematology Department at Hospital Clínic, represented by Dr. Emili Montserrat, leads an article published in Blood in which new recommendations have been formulated for the treatment of severe forms of Chronic Lymphocytic Leukemia. These recommendations have focused on choosing the best therapeutic strategy in each case, which will be very helpful for both professionals and patients. Read the rest of this entry »

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Wednesday October 15th, 2014

A combined therapy improves survival in patients with metastatic melanoma

According to an international multicenter study published in the New England Journal of Medicine (NEJM), in which the Hospital Clínic has participated, the combined treatment with BRAF and MEK inhibitors increases survival in patients with metastatic melanoma. Dr. Ana Arance, senior specialist at the Medical Oncology Department (ICMHO), is one of the authors.

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Monday October 6th, 2014

IDIBAPS at CCCB: Helping to decipher the brain

On 30 September, as part of the “Big Bang Data” exposition at the Center of Contemporary Culture of Barcelona (CCCB), Dr. Albert Compte, head of the IDIBAPS team Theoretical Neurobiology of Cortical Circuits and Dr. Jaime de la Rocha, researcher at the same group, taught the workshop “Helping  to decipher the brain? Large-scale projects to decipher the brain“. The participants in this activity were able to see firsthand which tools are available for investigators in neurosciences and the use of large databases for advanced research in this field. They also contributed, through different applications, to know a little better how the brain works.

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Calreticulin mutations help diagnose occult myeloproliferative neoplasms in patients with splanchnic vein thrombosis

Myeloproliferative neoplasms (Fildadelfia chromosome-negative) are the most common cause of splanchnic vein thrombosis, but they are often masked. A study led by IDIBAPS has found that screening for mutations in the gene encoding calreticulin (CALR) increases the number of diagnoses of this type of cancer and may reduce the need for additional studies, such as bone marrow biopsy, in some patients. This is the first study to evaluate the frequency of these mutations in a large number of patients.

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Tuesday September 23rd, 2014

Art and science meet at the first workshop on scientific sketching at IDIBAPS

The August Pi i Sunyer Biomedical Research Institute (IDIBAPS) held on Saturday 20th September its first public workshop on urban natural drawing (sketching). The initiative promoted by IDIBAPS in collaboration with the Drawing on Location School was successful both in organization and participation. One hundred talented people for drawing and curiosity for science and an organizing a team of thirty people, gathered in this original open day.

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