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Friday July 18th, 2014

IDIBAPS is the Spanish entity with more activities funded by the Innovative Medicines Initiative

The report named “Spanish Participation in the Innovative Medicines Initiative (IMI)” has been recently published by the Center for Industrial Technological Development (CDTI). This report lists the main indicators of participation in 8 of the 11 IMI’s calls supported under the 7th Framework Programme.

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Monday July 14th, 2014

Hospital Clínic and Astellas Pharma promote training in liver transplantation

In the third edition of the Fellowship in Liver Transplant Surgery, Astellas Pharma has exclusively chosen the Liver Surgery and Transplantation Unit at the Hospital Clínic de Barcelona to train a specialist in this field. This year, Dr. Rocío García Pérez, a specialist in General and Digestive Surgery, has been awarded with the fellowship. Dr. Pérez started her formation on May 15th at the department led by Dr. Juan Carlos García-Valdecasas.

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Tuesday July 8th, 2014

IDIBAPS participates in the Graphene Flagship

In the context of the Graphene Week 2014, the European Commission announced that the Graphene Flagship, one of the largest European research initiatives, is doubling its size and now includes more than 140 organizations from 23 countries. IDIBAPS is one of new 66 partners of the consortium through the team of Maria Victoria Sánchez-Vives, MD, PhD, ICREA Research Professor and team leader of the IDIBAPS group Systems Neuroscience. Professor Sanchez-Vives joins the Neurographene project, coordinated by Rosa Villa, PhD, from the CIBER-BBN Biomonitoring Group at the Barcelona Microelectronics Institute (IMB-CNM), and whose aim is to validate graphene as a brain interface material and to develop devices for both recording neural activity and for brain stimulation. The other partner in this project is the Austrian company Guger Technologies.

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Friday July 4th, 2014

Type 2 diabetic patients are better controlled with insulin pumps

Efficacy results from the comparison between the use of insulin pumps and multiple injections (OpT2mise trial) could define how this treatment can help in the management of insulin-requiring Type 2 Diabetes. Data obtained after six months show that patients who used the pump therapy safely achieved better glucose control, with 20% less insulin and without significant differences in weight gain.

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Thursday July 3rd, 2014

A mutation in progenitor cells identified as origin and therapeutic target for cholangiocarcinoma

In recent years, cancer research has been focused on the identification of mutations in genes involved in tumor development. Nevertheless, the molecular pathways that contribute to the progression of the disease remain quite unknown. The journal Nature publishes a paper in which an international team of scientists, led by Nabeel Bardesy, PhD, from the Harvard Medical School, suggests that a mutation in the IDH enzyme (isocitrate dehydrogenase), that occurs in liver progenitor cells, promotes the progression of cholangiocarcinoma, a type of liver cancer. Josep M. Llovet, MD, PhD, ICREA Research Professor at the HCC Translational Research Lab of the Liver Unit at IDIBAPS and Director of Mount Sinai Liver Cancer Program at the Icahn School of Medicine at Mount Sinai (New York) has collaborated in the study together with Daniela Sia, PhD, and Helena Cornellà, members of the same research group.

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Wednesday May 21st, 2014

An UB research shows that cholesterol plays a key role in cell migration

From left to right, researchers Carles Enrich, Meritxell Reverter, Anna Álvarez Guaita, Ana García Melero, Carles Rentero and Elsa Meneses, at the Faculty of Medicine of UB.

A group of researchers led by professor Carles Enrich, Chief of  IDIBAPS‘ Endocytosis and Protein Intracellular Transit team and member of Cellular Biology, Immunology and Neurosciences UB Dept., have found that cholesterol plays a key role in cell mobility and tissue invasion. The results of the study prove that the accumulation of LDL cholesterol cells —the one carried by low-density lipoproteins— may play a crucial role in promoting cell mobility. On the contrary, high levels of HDL cholesterol —the one carried by high-density lipoproteins— may avoid cell propagation. This is a key study to better understand cancer metastasis, the process in which cancer cells invade healthy tissues, and foster the discussion on the relationship between cholesterol levels and cancer incidence. The paper is published in open access Cell Reports.

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